fluoxetine
long acting SSRI( selective serotonin reuptake inhibitor)
works for major depressive disorder, obsessive-compulsive disorder and generalized anxiety disorder
it can cause suicidal risk in young adult 25 or younger
beware when used with tamoxifen due to cyp2d6 interaction
serious side effects include serotonin syndrome, which causes high blood pressure, fast heart rate and fever
paroxetine
short acting SSRI (selective serotonin reuptake inhibitor)
as it is short- acting, it has the highest risk of withdrawal syndrome
so tapering off during discontinuation is recommended
venlafaxine
under the cllass of SNRI ( serotonin norpinephrine reuptake inhibitor)
works by blocking reuptake of serotonin and norpinephrine
amitriptyline
underthe class of TCA ( tricyclic antidepressant)
usually not preferrred as first line due to side effect
can cause sedation, anticholinergic and cardiac side effect
monitor potassium level to rule out hypo- k
bupropion
a type od DNRI (dopamine norepinephrine reuptake inhibitor)
apart from depression can also be used for smoking cessation
this drug may be preferred if minimizing the risk of antidepressant induced sexual dysfubction